Figure 7

Comparison of adult pig lung, muscle, and spleen chromatin accessibility profiles. (a) Principal components analysis of read alignments for each library shows that biological replicates of each tissue cluster together. (b) Overlap of ATAC-seq peaks that were detected in both biological replicates for each tissue; minimum 1 bp overlap between biological replicates and between peak sets for each tissue. (c) Normalized read depth of ATAC-seq libraries at two genes: Interleukin 16 (IL16), a modulator of T cell activation, and transgelin (TAGLN), an actin cross-linking protein.