Table 3 Protease accessibility to bait region of each protein.

From: Human PZP and common marmoset A2ML1 as pregnancy related proteins

 

Human

Marmoset

PZP

A2ML1

PZP

A2ML1

Aspartic acid-N endopeptidase

+

+

+

Aspartic acid-N endopeptidase + N-terminal glutamic acid

+

+

+

+

Chymotrypsin

+

+

+

+

Clostripain

+

+

+

+

Glutamyl endopeptidase

+

+

+

+

Lysyl endopeptidase

+

+

+

Peptidyl-Lys metalloendopeptidase

+

+

+

Pepsin

+

+

+

+

Prolyl-endopeptidase

+

+

+

Proteinase K

+

+

+

+

Staphylococcal peptidase I

+

+

+

+

Thermolysin

+

+

+

+

Trypsin

+

+

+

+

  1. PeptideCutter was used for in silico prediction of protease cleavage sites in protein sequences. Predicted cutting sites of each protease are shown in Supplemental Fig. 4.