Table 3 MICs (mg/mL) for Malassezia spp. evaluated with L-lysine and L-threonine and values for AB and Flz control (µg/mL).
From: New Therapeutic Candidates for the Treatment of Malassezia pachydermatis -Associated Infections
Strains | MIC L-lysine | MIC L-threonine | MIC to ABa | ||
|---|---|---|---|---|---|
Microdilution assays | |||||
M. pachydermatis CBS 1879b | 3.1 | >25 | 0.25 | ||
M. pachydermatis C1c | 3.1 | >25 | — | ||
M. pachydermatis M1c | 3.1 | >25 | — | ||
M. pachydermatis N1c | 3.1 | >25 | — | ||
Atypical M. furfurb | 3.1 | >25 | — | ||
M. sympodialis CBS 7222b | 3.1 | >25 | — | ||
M. furfur CBS 1878b | 1 | >25 | 4 | ||
C. krusei ATCC 6258b | — | — | 2 | ||
C. parapsilosis ATCC 22019b | — | — | 0.25 | ||
E-test® method | |||||
Strain | Flza | ABa | |||
M. pachydermatis CBS 1879b | 48–64 | 1–2 | |||
M. pachydermatis N1c | 64–128 | 3–6 | |||
M. pachydermatis M1c | 8–16 | 3–4 | |||
M. pachydermatis C1c | 4 | 8 | |||
M. furfur CBS 1878b | 3–4 | >32 | |||
M. sympodialis CBS 7222b | 0.75–1.5 | 2 | |||