Figure 6
From: The Transcription Factor-microRNA Regulatory Network during hESC-chondrogenesis
Transcription factors and microRNAs regulating co-expressed clusters of genes during chondrogenesis. X-Y scatter plot showing the odds ratio (y-axis) and P-value (x-axis) for the enrichment of targets of each TF (A) or microRNA (B) within a co-expressed cluster calculated using a Fisher’s Exact Test. (C) Venn diagram showing overlap of TFs (C) or microRNA (D) with an enrichment of targets within the ECM cluster (P-value < 0.001 and Odds ratio >1) (center) and if they are significantly up-regulated (left) or down-regulated (right) during hESC-chondrogenesis. Expression of significantly upregulated TFs (E) or microRNA (F) with the highest enrichment of targets within the “ECM Organisation’ cluster during differentiation.
