Table 1 Clinical descriptors of the full cohort and according to the Hoehn & Yahr disease stages two to four.

From: High-Resolution Motor State Detection in Parkinson’s Disease Using Convolutional Neural Networks

parameter

full cohort

HY stage 2

HY stage 3

HY stage 4

 

N or mean ± SD (range)

Gender (male/female)

20/10

9/2

9/7

2/1

Age (years)

67.1 ± 10.2 (40–83)

66.1 ± 8.1 (47–73)

69.5 ± 11.0 (40–83)

58.0 ± 9.2 (48–66)

Disease duration (years)

11.0 ± 5.1 (1–21)

9.9 ± 6.0 (1–18)

11.2 ± 4.8 (2–21)

14.3 ± 2.3 (13–17)

Levodopa equivalent dose$

1109 ± 785 (90–3754)

1172 ± 1113 (90–3754)

1053 ± 521 (120–2435)

1181 ± 806 (675–2110)

MDS-UPDRS III (ON)

21.6 ± 15.3 (2–57)

16.9 ± 15.8 (2–57)

25.4 ± 15.6 (5–54)

19.0 ± 7.9 (13–28)

AIMS

(sum items 1–7)

2.1 ± 2.4 (0–7)

1.2 ± 1.8 (0–4.5)

2.5 ± 2.7 (0–7)

2.9 ± 2.7 (1.25–6.0)

Montreal Cognitive Assessment

25.7 ± 2.8 (18–30)

26.1 ± 1.9 (24–30)

24.9 ± 3.3 (18–29)

28.0 ± 1.7 (27–30)

Body Mass Index (kg/m2)

25.2 ± 4.8 (12.9–35.4)

26.9 ± 5.0 (21.6–35.4)

25.2 ± 3.9 (21.3–35.1)

19.4 ± 5.8 (12.9–23.7)

Duration of motion data recording (hours)

7.5 ± 3.9 (0.4–13.4)

6.6 ± 4.0 (0.4–12.5)

8.3 ± 3.8 (2.8–13.4)

6.5 ± 5.1 (2.6–12.3)

Additional therapy, i.e. deep brain stimulation (DBS) or continuous subcutaneous apomorphine infusion (CSAI)

DBS = 4

CSAI = 2

DBS = 1

DBS = 1

CSAI = 2

DBS = 2

  1. Mean ± standard deviation is given with the range in brackets. $Levodopa equivalent dose is calculated according to ref. 68. Abbreviations: AIMS, abnormal involuntary movement scale; UPDRS, unified PD rating scale; DBS, deep brain stimulation; CSAI, continuous subcutaneous apomorphine infusion.