Figure 1

Taurine concentration in serum and liver, and histological observations of hepatic tissue. (A) Progress of serum taurine concentration during the experimental diet feeding for 30 weeks. (B) Taurine and glycine concentrations in the liver after the 30-week feeding. (C) H&E stain of hepatic tissue; (Ca & Cb) Overall hepatic lobule (objective × 4) and the portal region (×10) images in the Control group. (Cc & Cd) Overall hepatic lobule (×4) and the portal region (×10) images in the Depletion group. C and P in Fig. 1Cb and Cd show the central vain and portal vain, respectively. Data are the mean ± SE. *P < 0.05, **P < 0.01, †P < 0.001 versus the Control group at each point by unpaired Student t-test.