Table 2 Expression of the serum biomarkers between CRS and CHF groups.

From: Circulating miRNA-21 as a diagnostic biomarker in elderly patients with type 2 cardiorenal syndrome

Characteristics

CHF Group (n = 73)

CRS Group (n = 84)

P

NT-proBNP (ng/L)

1739 (3332)

5332 (6820)

<0.001

KIM-1 (pg/ml)

82.23 (94.05)

127.5 (157.76)

0.006

NGAL(ng/ml)

89.3 (48.3)

130.15 (92.07)

<0.001

Cys C (mg/L)

1.14 (0.31)

2.0 (0.95)

<0.001

NAG (nmol)

14.5 (4.9)

15.28 (8.51)

0.166

H-FABP (pg/ml)

1469.97 (1739.88)

2677.9 (4191.8)

<0.001

eGFR (mL/min/1.73 m2)

74.13 ± 1.07

43.23 ± 1.64

<0.001

miR-21

0.53 (0.44)

0.89(0.89)

<0.001

  1. Data are expressed as Median (Quartile range) or Mean ± Standard deviation
  2. CRS: type 2 Cardio-Renal syndrome; miR-21: MicroRNA-21; CHF: chronic heart failure; eGFR: estimated glomerular filtration rate; KIM-1: idney injury factor-1; NGAL: neutrophil gelatinase-related apolipoprotein; Cys C: cystatin C; NT-proBNP: amino-terminal pro-B-type natriuretic peptide; NAG: N-acetyl-κ-D-glucosaminidase; H-FABP: heart-typefatty acid–binding protein. P < 0.05 has statistically significant.
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