Figure 6
From: Time course of bilateral microglial activation in a mouse model of laser-induced glaucoma
P2RY12 expression in ocular hypertension (OHT) eyes in the outer plexiform layer (OPL) at different times after laser-induced OHT (1, 3, 5, 8 and 15 d). Double immunostaining: Iba-1 (A,D,G,J,M), P2RY12 (B,E,H,K,N), merge (C,F,I,L,O). Retinal whole-mounts. At 1 d after laser induction, most Iba-1+ cells intensely expressed P2RY12. This expression was strongly reduced at 3 and 5 d (arrowheads); it increased weakly at 8 d, reaching values similar to those of naïve eyes at 15 d.
