Figure 1

AGS-004–009 Study Design. A) Overall study design. Resting CD4⁺ T cell-associated HIV gag RNA was measured at baseline, after the single dose, the paired dose and the first and second cycle of VOR plus AGS-004. RCI was measured at baseline, and after the first and second cycle of VOR+ AGS-004. X details immune monitoring (IM) sample collection to determine immune responses by multi-color flow cytometry. X denotes the timepoints of blood draw collection. The purple X (Visit 10) represents the time point before the administration of AGS-004 and serves as the baseline prior to immunological measurements (unless otherwise noted in a given figure).