Figure 3 | Scientific Reports

Figure 3

From: Rhein, a novel Histone Deacetylase (HDAC) inhibitor with antifibrotic potency in human myocardial fibrosis

Figure 3

Influence of Rhein administration on transcriptomic profiles in cardiac fibroblasts under normoxic and hypoxic conditions. (A) Graph showing the global top 15 canonical pathway annotations of differential transcripts sorted by cumulative −Log10 p-value. (B) Graph showing the global top 15 predicted upstream regulators of differential transcripts sorted by cumulative −Log10 p-value. N: Normoxia, H: Hypoxia, NR: Normoxia + Rhein, HR: Hypoxia + Rhein.

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