Figure 5

Electrical linear filters vary with light response profiles of RGCs. (a) Distribution of cells according to their light response profile. Color codes for cluster assignment of a cell based on its electrical linear filter. Grey dots indicate cells which were not included in the clustering due to below-threshold response reliability in the electrical stimulation condition (\(RI < 0.15\)). Bias Index quantifies the polarity of the light response from OFF (−1) through ON-OFF (around 0) to ON (1); Transiency Index quantifies duration of the response to a cell’s preferred light stimulus from sustained (0) to transient (1). (b–h) Example cells with different light response profiles, indicated in (a) by larger dots. Upper plot in each panel shows a raster plot of the cell’s light response in 4–10 repetitions of the light step stimulus. Light onset is indicated by a vertical red line. Lower plot in each panel shows the cell’s electrical linear filter as estimated by STA in the LNP model; color coding as in panel a. Vertical line indicates spike time. The timescale bar corresponds to 200 ms in the upper plot, and to 6 ms in the lower plot.