Table 1 Changes of blood biochemical parameters in rats.

From: Identification of metabolite biomarkers in serum of rats exposed to chlorpyrifos and cadmium

Groups

Parameters

ALT (U/L)

AST (U/L)

TBIL (µM)

BUN (mM)

CRE (µM)

Control

33.00 ± 0.77bc

112.33 ± 6.77b

0.25 ± 0.19d

5.27 ± 0.07 cd

24.33 ± 1.29b

CPF-L

32.75 ± 1.80bc

142.75 ± 2.46ab

0.10 ± 0.04d

5.67 ± 0.05abcd

25.75 ± 0.67b

CPF-M

34.00 ± 2.71bc

157.67 ± 11.66a

0.47 ± 0.09 cd

5.34 ± 0.23bcd

27.40 ± 0.87ab

CPF-H

36.67 ± 1.86abc

142.75 ± 10.23ab

1.65 ± 0.21a

5.01 ± 0.08 cd

26.00 ± 1.93b

Cd-L

34.75 ± 1.23bc

148.25 ± 6.68ab

0.33 ± 0.14d

5.57 ± 0.26abcd

23.50 ± 0.58b

Cd-M

34.00 ± 1.18bc

158.00 ± 9.71a

1.17 ± 0.23abc

6.47 ± 0.37a

26.00 ± 0.77b

Cd-H

41.50 ± 3.38a

152.67 ± 8.27a

0.95 ± 0.24abc

6.30 ± 0.31ab

32.50 ± 2.08a

CPF-L + Cd-L

34.25 ± 0.43bc

170.50 ± 14.12a

0.90 ± 0.25abc

5.01 ± 0.15 cd

27.40 ± 1.94ab

CPF-M + Cd-L

31.80 ± 0.80bc

164.50 ± 8.05a

0.77 ± 0.14 cd

5.38 ± 0.18bcd

26.60 ± 1.50ab

CPF-H + Cd-L

32.75 ± 3.27bc

166.00 ± 15.38a

0.93 ± 0.24abc

5.94 ± 0.27abc

26.00 ± 0.97b

CPF-L + Cd-M

31.25 ± 0.99c

128.50 ± 6.71b

1.77 ± 0.41ab

5.73 ± 0.06abcd

27.50 ± 1.88ab

CPF-M + Cd-M

37.25 ± 2.64abc

149.75 ± 16.80ab

1.35 ± 0.24ab

5.02 ± 0.16 cd

25.25 ± 1.88b

CPF-H + Cd-M

36.33 ± 1.69abc

168.67 ± 8.12a

0.23 ± 0.07d

5.42 ± 0.40bcd

28.00 ± 2.99ab

CPF-L + Cd-H

39.20 ± 2.11ab

153.20 ± 14.92ab

1.30 ± 0.39abc

5.14 ± 0.33 cd

28.20 ± 0.80ab

CPF-M + Cd-H

37.75 ± 1.95ab

167.00 ± 14.59a

1.43 ± 0.25abc

4.82 ± 0.53d

27.25 ± 2.32ab

CPF-H + Cd-H

41.00 ± 2.10a

218.33 ± 27.36a

0.97 ± 0.07bc

4.79 ± 0.29d

26.80 ± 1.83ab

  1. Note: Data were expressed as mean ± SE and differences among the groups evaluated by ANOVA. Different superscripted letters indicate a significant difference among the groups (P < 0.05), while the same letters indicate no significant difference among the groups (P > 0.05). Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; BUN, blood urea nitrogen; CRE, creatinine; TBIL, total bilirubin; BW, body weight; L, low dose; M, middle dose; H, high dose.