Figure 4
From: Tumor fitness, immune exhaustion and clinical outcomes: impact of immune checkpoint inhibitors

Distribution of MHC-I binding affinities for tumor neoepitopes (dotted line) and HBV epitopes (solid line). Smaller ic50 values indicate a stronger binding affinity. Tumor neoepitopes are on average more likely to bind to patient MHC-I alleles than epitopes from HBV proteins.