Figure 3

Effects of EGCG and nano-EGCG on the cell invasion and migration of H1299 and A549 cells. The effects of different concentrations of nano-EGCG (A) and EGCG (B) on the invasive capabilities of H1299 cells were determined. The cell migration ability of H1299 cells treated with nano-EGCG (C) or EGCG (D) was assessed through scratch wound-healing assays. The number of cells that migrated into the cell-free zone was evaluated at 4, 8, and 12 hours after wounding. The effects of nano-EGCG on the cell invasion (E) and migration (F) abilities of A549 cells were also determined. The data are representative of three independent experiments and are indicated as the mean ± SD. *P < 0.05 compared with the control group.