Table 1 Identification of dysregulated genes in foci.

From: Transformation Foci in IDH1-mutated Gliomas Show STAT3 Phosphorylation and Downregulate the Metabolic Enzyme ETNPPL, a Negative Regulator of Glioma Growth

Gene Symbol

Description

DLGG (log2)

Foci (log2)

Fold Change (DLGG/foci)

p-value

SFRP2

Secreted Frizzled Related Protein 2

6.51

5.5

2

0.0475

CST3

Cystatin C

8.94

8.1

1.79

0.0277

DAAM2

Dishevelled Associated Activator Of Morphogenesis 2

7.2

6.4

1.75

0.0253

ETNPPL

Ethanolamine-Phosphate Phospho-Lyase

6.01

5.22

1.72

0.0096

TMEM47

Transmembrane Protein 47

6.16

5.48

1.61

0.0126

MLC1

Megalencephalic Leukoencephalopathy With Subcortical Cysts 1

6.86

6.23

1.54

0.0028

KCNN3

Potassium Calcium-Activated Channel Subfamily N Member 3

6.42

5.8

1.54

0.0377

ADCYAP1R1

Adenylate Cyclase Activating Polypeptide 1 (Pituitary) Receptor Type I

7.28

6.72

1.47

0.0116

GJA1

Gap Junction Protein Alpha 1

5.79

5.27

1.43

0.0223

EZR

Ezrin

6.98

6.46

1.43

0.0048

ALDOC

Aldolase, Fructose-Bisphosphate C

7.81

7.36

1.37

0.0107

ATP1A2

ATPase Na + /K + Transporting Subunit Alpha 2

6.88

6.47

1.33

0.0072

SLC1A3

Solute Carrier Family 1 Member 3

5.96

5.57

1.32

0.0273

  1. Fold changes (DLGG/foci) are indicated. p-values (ANOVA unpaired tests, n = 8 cases) are indicated.
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