Table 3 Mean performance using the standard grading system, logistic regression (LR), and Artificial Neural Network (ANN) to predict surgical resectability in patients with glioblastoma.
Parameter | Estimate (95% CI) | P value |
|---|---|---|
Accuracy | ||
ANN | 83.4 (81.6–85.1) | <0.01 |
LR | 83.2 (81.3–85.0) | <0.01 |
Standard grading system | 80.2 (78.2–82.1) | Reference |
AUC | ||
ANN | 0.871 (0.849–0.895) | <0.01 |
LR | 0.868 (0.848–0.889) | <0.01 |
Standard grading system | 0.786 (0.747–0.825) | Reference |
Sensitivity | ||
ANN | 0.586 (0.531–0.640) | 0.0861 |
LR | 0.587 (0.532–0.643) | 0.0807 |
Standard grading system | 0.543 (0.489–0.560) | Reference |
Specificity | ||
ANN | 0.915 (0.898–0.932) | 0.0117 |
LR | 0.910 (0.893–0.927) | 0.0380 |
Standard grading system | 0.885 (0.861–0.908) | Reference |
PPV | ||
ANN | 0.707 (0.649–0.766) | 0.0164 |
LR | 0.679 (0.619–0.739) | 0.236 |
Standard grading system | 0.642 (0.585–0.698) | Reference |
NPV | ||
ANN | 0.877 (0.862–0.892) | 0.0945 |
LR | 0.878 (0.862–0.893) | 0.0677 |
Standard grading system | 0.864 (0.849–0.880) | Reference |