Table 1 Overview of Clinical Findings in All Animals.

From: Lentiviral Vector Induced Modeling of High-Grade Spinal Cord Glioma in Minipigs

Animal

Baseline

Endpoint

Injection Site

Weight (kg)

mTS

Hindlimb Motor Deficits

Superficial Pain Response

Conscious Proprioception

Gastrointestinal Genitourinary

Weight (kg)

mTS

1

R: ONC

20.2

9

Right

R: Delayed

R: Delayed

WNL

20.4

8

L: CTRL

2

R: CTRL

19.7

9

Bilat

R: Absent

R: Absent

Urine Retention

21.8

0

L: ONC

L: Absent

L: Absent

3

R: ONC

15.3

9

Bilat

WNL

R: Absent

WNL

16.4

3

L: CTRL

L: Absent

4

R: CTRL

15.5

9

Left

WNL

L: Delayed

WNL

15.4

8

L: ONC

5

R: ONC

21.6

9

Right

R: Delayed

R: Absent

WNL

21.1

8

L: CTRL

6

R: CTRL

17.2

9

Left

WNL

WNL

WNL

18.1

8

L: ONC

  1. Abbreviations: R – right, L – left, ONC – oncogenic vectors, CTRL – control vectors, Bilat – bilateral, GI/GU – Gastrointestinal or Genitourinary, WNL – within normal limits, mTS – modified Tarlov Score.