Figure 1

ITIH3 expression in brain subtissues across brain development (with RNA-seq RPKM values from the BrainSpan Atlas v.10; shown from 8 postconception weeks (pcw) to 40 years of age (yrs)). Birth is indicated by a vertical gray dashed line, and the mean expression across all time points is indicated by a horizontal black dashed line. The Y-axis is log₂ (RPKM values). The brain structures are primary auditory cortex (core) (A1C), amygdaloid complex (AMY), cerebellar cortex (CBC), dorsolateral prefrontal cortex (DFC), hippocampus (HIP), posteroventral (inferior) parietal cortex (IPC), inferolateral temporal cortex (area TEv, area 20) (ITC), primary motor cortex (area M1, area 4) (M1C), mediodorsal nucleus of thalamus (MD), anterior (rostral) cingulate (medial prefrontal) cortex (MFC), orbital frontal cortex (OFC), primary somatosensory cortex (area S1, areas 3,1,2) (S1C), posterior (caudal) superior temporal cortex (area 22c) (STC), striatum (STR), primary visual cortex (striate cortex, area V1/17) (V1C), and ventrolateral prefrontal cortex (VFC).