Figure 1 | Scientific Reports

Figure 1

From: Enhanced glycolysis and HIF-1α activation in adipose tissue macrophages sustains local and systemic interleukin-1β production in obesity

Figure 1

(a–d) Seahorse analysis of cellular (a) oxygen consumption rate (OCR), (b) basal respiration, maximum respiration and spare respiratory capacity, (c) extracellular acidification rate (ECAR), and (d) glycolysis, glycolytic capacity and glycolytic reserve, in ATM from lean and obese wild type (WT) mice. Data are representative of 2 independent experiments from n = 2–3 mice/group. (e) Lactate levels in the stromal vascular fraction (SVF) of lean (n = 4) and obese mice (n = 5). (f) Serum lactate levels in lean (n = 6) and obese (n = 9) mice. Data are expressed as mean ± s.e.m. **p < 0.01, *p < 0.05.

Back to article page