Table 1 Affinities of TUDC and norUDCA and the control peptide towards the RGD-recognizing integrin α5β1 obtained from an ELISA-like solid-phase binding assay.

From: Evidence for functional selectivity in TUDC- and norUDCA-induced signal transduction via α5β1 integrin towards choleresis

Compound

Sequence

IC50a

TUDC

—

4.01 (1.80…8.98)b

norUDCA

—

3.93 (1.34…11.5)b

Control peptide Cilengitide

c(Arg-Gly-Asp-d-Phe-NMe-Val)

15.4 (14.49…16.36)c

  1. aThe IC50 values were obtained from a sigmoidal fit to two independent data rows (serial dilutions). The 95% confidence interval is given in brackets.
  2. bIn mM.
  3. cIn nM.
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