Figure 10
From: Cellular processes involved in lung cancer cells exposed to direct current electric field
Genetic alterations of the hub genes were analyzed using the cBioPortal. (A) Genetic alterations of the hub genes were analyzed using cBioPortal. Grey bars along a vertical line represent the same sample interrogated for amplification (red), deep deletion (blue), missense mutation (green), truncating mutation (black) or Fusion (purple). (B) The alteration frequency of a 10-gene signature (EGFR, JUN, ITGA2, FGF2, CCND1, IL6, MMP9, MAPK13, KRAS and NRAS) was determined using the cBioPortal (http://www.cbioportal.org). (C) Overall Survival Kaplan–Meier estimate. (D) Relative expression level as a function of relative copy number of EGFR was plotted in different databases. (E) The distribution of EGFR mutations in non–small-cell lung cancer across protein domains.
