Table 1 Characteristics of 211 adult patients with previously untreated (N = 211) non-M3-AML.
Characteristics | Median | Range |
|---|---|---|
Age (yrs) | 64 | 19–88 |
Marrow blasts (%) | 70 | 4–99 |
WBC (109/L) | 29.6 | 0.8–274 |
Peripheral blasts (%) | 38 | 0–99 |
Hemoglobin (g/dL) | 9.1 | 4.3–13.7 |
Platelets (109/L) | 58.5 | 2–1052 |
Number | % | |
Sex: | ||
Female | 94 | 45 |
Male | 117 | 55 |
Race/Ethnicity: | ||
Native American | 1 | 0.5 |
Asian, Pacific Islander | 7 | 3 |
Black, African American | 17 | 8 |
White/Hispanic | 5 | 2 |
White/Non-Hispanic | 179 | 85 |
Hispanic, NOS | 2 | 1 |
AML Onset (months): | ||
De Novo | 170 | 81 |
Secondary | 41 | 19 |
FAB Class (local diagnosis): | ||
M1 | 47 | 22 |
M2 | 78 | 37 |
M4 | 46 | 22 |
M5 | 22 | 10 |
M6 | 1 | 0.5 |
M7 | 2 | 1 |
M0 | 9 | 4 |
Other | 5 | 2 |
Performance Status | ||
0 | 63 | 30 |
1 | 104 | 49 |
2 | 25 | 12 |
3 | 17 | 8 |
Unknown | 2 | 1 |
Cytogenetics Evaluated: | ||
Yes | 169 | 80 |
No | 42 | 20 |
Karyotype Category:* | ||
Normal | 78 | 46 |
t(8:21) | 7 | 4 |
inv(16)/t(16;16) | 7 | 4 |
−5/del(5q) | 7 | 4 |
−7/del(7q) | 9 | 5 |
Other | 9 | 5 |
Study | ||
S9031 | 75 | 36 |
S9126 | 10 | 5 |
S9333 | 81 | 38 |
S9500 | 45 | 21 |
