Table 1 Clinical features presentation between AMS and Non-AMS group.

From: EDN1 gene potentially involved in the development of acute mountain sickness

 

Total

AMS (n=237)

Non-AMS (n=119)

Wilcox/T*/Fisher& test

Age (years old)

23.05 ± 3.99

23.44 ± 4.17

22.28 ± 3.48

0.15

BMI

21.72 ± 2.31

21.83 ± 2.42

21.50 ± 2.08

0.32

Smoking

 

64/1/172

34/0/85

0.87&

Alcohol

 

1/82/154

0/36/83

0.61&

SBP (mmHg)

117.85 ± 11.64

117.89 ± 11.78

117.77 ± 11.39

0.65

DBP (mmHg)

78.35 ± 9.89

78.39 ± 9.61

78.28 ± 10.48

0.92*

MAP (mmHg)

91.51 ± 9.99

91.54 ± 9.87

91.45 ± 10.27

0.94*

SaO2 (%)

88.15 ± 3.16

87.42 ± 3.09

89.61 ± 2.77

<0.001

HR

82.32 ± 12.49

83.7 ± 12.31

79.56 ± 12.44

<0.01*

FVC

4.00 ± 0.43

3.82 ± 0.37

4.35 ± 0.31

<0.001

FVC % predicted

 

88.17 ± 8.76

94.51 ± 6.82

<0.001

FEV1

3.47 ± 0.31

3.38 ± 0.29

3.67 ± 0.26

<0.001

FEV1%predicted

 

82.23 ± 6.03

84.94 ± 6.45

0.124

PEF

9.24 ± 0.68

9.20 ± 0.67

9.33 ± 0.70

0.09

V75

8.17 ± 0.77

8.17 ± 0.81

8.16 ± 0.89

0.72

V50

4.75 ± 0.41

4.65 ± 0.37

4.95 ± 0.42

<0.001

V25

2.16 ± 0.18

2.10 ± 0.15

2.27 ± 0.19

<0.001

MMF

4.38 ± 0.37

4.29 ± 0.36

4.56 ± 0.32

<0.001

Headache

 

4/161/61/11

70/49/0/0

<0.001&

Dizziness

 

11/173/46/7

72/47/0/0

<0.001&

Gastrointesti0l

 

146/67/23/1

116/3/0/0

<0.001&

Fatigue

 

4/171/51/11

82/36/1/0

<0.001&

Tryptophan(ng/ml)

61.49 ± 9.19

66.99 ± 4.56

50.55 ± 5.49

<0.001

Serotonin(pg/ml)

0.98 ± 0.19

1.07 ± 0.16

0.80 ± 0.09

<0.001

  1. “/” represent different statistical method for selection. Fisher Exact Test&, T test* and Wilcox test. BMI, Body Mass Index; SBP, systolic blood pressure; DBP, diastolic blood pressure; MAP, Mean artery pressure; HR, heart rate; FVC, forced expiratory volume; FEV1, forced expiratory volume in 1 second; PEF, peak expiratory flow; V75, 75% vital capacity; V50, 50% vital capacity; V25, 25% vital capacity; MMF, mean maximal flow.
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