Table 3 Multimarker haplotype (rs5370-rs2070699-rs2248580) analysis within the EDN1 gene region in AMS and Non-AMS subjects.

From: EDN1 gene potentially involved in the development of acute mountain sickness

Haplotype

Frequency in AMS

Frequency in Non-AMS

χ2 (1 df)

P (adjust)

TGC

0.26

0.31

2.30

0.13

GGC

0.11

0.11

7.1 × 10−7

1.00

GGA

0.06

0.12

7.09

0.01

GTA

0.57

0.46

7.81

0.005

  1. Globe χ2 = 11.85; df = 3; P = 0.008.
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