Table 1 Baseline traits of study participants.

From: Systemic inflammation is associated with incident stroke and heart disease in East Asians

Trait

Controls (n = 5285)

Major Coronary Events (n = 1508)

Ischemic Stroke (n = 5418)

Intracerebral Hemorrhage (n = 4476)

Age and Sociodemographic factors

Age, y*

55.8 (10.9)

56.5 (9.72)

55.4 (9.36)

59.3 (10.1)

Female, %

49.6

41.6

55.6

49.9

Rural, %

79.2

66.6

54.6

79.5

Middle School and above, %

38.3

36.8

38.2

36.0

Income > 10,000 yuan/year, %

62.2

61.5

65.6

62.5

Lifestyle factors

Male smokers, %

87.1

90.9

89.5

86.9

Female smokers, %

3.9

7.8

5.4

5.9

Male regular drinkers, %

32.1

26.5

30.9

33.1

Female regular drinkers, %

2.1

1.8

2.2

2.1

Physical activity, MET h/day

20.1 (11.8)

18.7 (11.6)

18.7 (11.5)

19.0 (11.6)

Anthropometric, blood pressure and circulatory measures

Standing height, m

1.59 (0.06)

1.59 (0.06)

1.59 (0.06)

1.58 (0.06)

BMI, kg/m2

23.4 (3.1)

23.9 (3.4)

24.1 (3.4)

23.8 (3.4)

Waist-hip ratio

0.89 (0.07)

0.91 (0.07)

0.90 (0.07)

0.90 (0.07)

SBP, mmHg

134.4 (19.7)

143.6 (25.1)

144.4 (23.9)

152.9 (27.3)

DBP, mmHg

78.5 (11.0)

83.0 (13.3)

83.9 (12.5)

88.5 (14.2)

Heart rate, per minute

78.3 (11.7)

80.4 (12.7)

79.2 (12.1)

79.9 (12.6)

Markers of subclinical atherosclerosis

Plaque, %

39.9

60.5

50.7

44.4

cIMT, mm

0.71 (0.13)

0.78 (0.23)

0.75 (0.16)

0.72 (0.16)

Inflammatory biomarkers

CRP, mg/L§

0.90 (0.86–0.93)

1.31 (1.24–1.39)

1.12 (1.08–1.16)

1.08 (1.04–1.13)

Fibrinogen, g/L§

3.00 (2.98–3.03)

3.07 (3.04–3.11)

3.05 (3.02–3.08)

3.02 (2.99–3.05)

Lipids

Triglycerides§, mg/dL

145.8 (143.1–148.5)

163.4 (158.5–168.5)

156.6 (153.9–159.45)

145.5 (142.7–148.5)

LDL cholesterol?, mg/dL

91.6 (23.9)

95.9 (29.1)

95.9 (25.8)

90.8 (26.4)

Self-reported health and disease

Poor self-rated health, %

8.1

18.4

14.6

15.5

Hypertension, %

10.4

21.7

23.7

26.4

Diabetes, %

6.0

14.0

12.4

9.3

  1. CRP: C-reactive protein; cIMT: carotid intima-media thickness; DBP: Diastolic Blood Pressure; ICH: Intracerebral hemorrhage; IS: Ischemic stroke; LDL: Low-density lipoprotein; MET: metabolic equivalents; SBP: Systolic Blood Pressure.
  2. Values are mean (standard deviation) for continuous traits or proportion (weighted percentage) for binary/categorical traits, standardized to age, sex and study area of case-control cohort unless otherwise stated.
  3. *Standardized to sex and study area only.
  4. Standardized to age and study area only.
  5. Standardized to age and sex only.
  6. §Geometric mean (95% CI). ?Note: Low-density lipoprotein (LDL) cholesterol was directly measured.