Table 2 Expression miRNAs important in heart development and diseases of foetuses heart from BPA-exposed pregnant rats.

From: The impacts of intrauterine Bisphenol A exposure on pregnancy and expression of miRNAs related to heart development and diseases in animal model

miRNAs

BPA concentration (ppm)

Mother

p-value

Foetus

p-value

miR-15b-3p

5

0.400 ± 0.339

0.491

1.463 ± 0.201

0.058

20

0.494 ± 0.284

0.982 ± 0.534

miR-17-5p

5

0.814 ± 0.368

0.268

1.475 ± 1.139

0.027*

20

0.793 ± 0.369

2.257 ± 1.343

miR-21-5p

5

0.806 ± 0.278

0.371

1.459 ± 0.270

0.068

20

0.609 ± 0.222

1.009 ± 0.189

miR−133a-3p

5

1.489 ± 3.391

1.000

0.431 ± 0.723

0.073

20

1.817 ± 2.880

1.916 ± 2.974

miR-208a-3p

5

1.305 ± 43.717

0.985

0.656 ± 1.517

0.039*

20

1.932 ± 48.973

4.301 ± 13.191

miR-499-5p

5

1.794 ± 0.599

0.005*

0.900 ± 0.584

0.593

20

2.255 ± 0.448

1.291 ± 0.241

miR-210-3p

5

0.840 ± 0.585

0.679

1.104 ± 0.619

0.039*

20

0.977 ± 0.412

2.698 ± 1.249

miR-30a-5p

5

1.588 ± 2.677

0.564

0.874 ± 0.397

0.273

20

2.262 ± 3.411

1.683 ± 1.096

  1. Values presented as mean ± SEM, n = 5. p-values generated from Non parametric Study Kruskal Wallis Test.
  2. *Indicates treatment significantly different from baseline, p < 0.05.
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