Figure 8
From: Gradual wiring of olfactory input to amygdala feedback circuits
Responses of PmCo corticobulbar neurons to urine odor stimuli. (A) Sagittal section of the PmCo showing c-Fos/Ct-b colabeling (insets are magnified from the region highlighted in yellow). (B) Comparison of c-Fos expression in the whole PmCo after exposure to home-cage odors (ctrl), male (MU) or female (FU) urine stimuli in juvenile (P25) and mature (P50) female mice. Male odors do not activate significantly PmCo neurons in juvenile females, but female odors do. Conversely, male odors activate PmCo neurons more than female odors in mature female mice. (C) Quantification of c-Fos expression in Ct-b-positive PmCO neurons (ACPs) in response to the same odor sources, in the same mice. ACPs do not show sex-specific responses in juvenile female mice. ACPs show sex specific odor responses in mature female mice. (D) Effect of mature (P50) experience in ACP odor responses. Exposure to homecage odors is compared to novel (nMU), familiar (fMU) and unfamiliar (uMU) odors. Size of each sample is indicated on the relative histogram bar. Data are expressed as mean ± SEM. Scale bars 50 μm, 200 μm. See Table 2 for the results of the statistical tests.
