Figure 1

mRNA expression level of ST2 and FoxP3 in the adenomas and CRC tissues. The mRNA expression level of ST2 determined by real-time PCR was significantly increased in the adenoma tissues (grey bar in A) compared to the normal controls (white bar in A, P < 0.05). It was also significantly higher in the CRC tissues (black bar in A) than in the normal controls (white bar in A, P < 0.05) but slightly lower than that in the adenoma tissues (grey bar in A). As seen in B, the expression level of FoxP3 mRNA showed an increasing trend along the adenoma-carcinoma sequence. Increased expression of FoxP3 mRNA was started from the adenoma stage (grey bar in B) and even higher in the CRC stage (black bar in B) compared to the normal controls (white bar in B, both P < 0.05). NS: no significant, P > 0.05.