Figure 2 | Scientific Reports

Figure 2

From: N-Phenethyl Substitution in 14-Methoxy-N-methylmorphinan-6-ones Turns Selective µ Opioid Receptor Ligands into Dual µ/δ Opioid Receptor Agonists

Figure 2

Time- and dose-dependent antinociceptive effects of 14-methoxy-N-methylmorphinan-6-ones 14-OMO (3) and 14-MM (4) and their respective N-phenethyl analogues 3a and 4a in the tail-flick assay in mice after s.c. administration. Data are shown as the mean %Maximum Possible Effect (%MPE) ± SEM (n = 5–6 mice per group).

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