Table 1 Clinical and tumor profile of 3453 patients with early breast cancer.
Characteristics | N | n (%) |
|---|---|---|
Median age in years (Range) | 3453 | 53 (20–89) |
Sex | 3453 | |
Female | 3403 (98.6) | |
Male | 50 (1.4) | |
Menstrual status | 3394 | |
Postmenopausal | 2038 (60) | |
Premenopausal | 1356 (40) | |
Primary side | 3429 | |
Left | 1749 (51) | |
Right | 1680 (49) | |
Histology | 3453 | |
IDC or IBC NOS | 3246 (94) | |
ILC | 79 (2.3) | |
Medullary | 11 (0.3) | |
Mucinous | 61 (1.8) | |
Others | 56 (1.6) | |
pT Size in cm | 3269 | |
<2 cm | 670 (20.5) | |
2.1–3 cm | 1323 (40.5) | |
3.1–5 cm | 1037 (31.7) | |
>5.1 cm | 239 (7.3) | |
Pathological stage | 3379 | |
I | 397 (11.8) | |
IIA | 1381 (40.9) | |
IIB | 876 (25.9) | |
IIIA | 427 (12.6) | |
IIIC | 298 (8.8) | |
Grade | 3293 | |
1 | 299 (9.1) | |
2 | 1640 (49.8) | |
3 | 1354 (41.1) | |
Lymphatic invasion | 3227 | |
No | 2186 (67.7) | |
Yes | 1041 (32.3) | |
Positive nodes | 3413 | |
Zero | 1788 (52.4) | |
1–3 | 949 (27.8) | |
4–9 | 398 (11.7) | |
>10 | 278 (8.1) | |
Positive node ratio | 1625 | |
Median | 0.15 (0.02–1.0) | |
Extra capsular spread in node positive | 1474 | |
Negative | 772 (52.4) | |
Positive | 702 (47.6) | |
ER | 3421 | |
Negative | 1228 (35.9) | |
Positive | 2193 (64.1) | |
PR | 3422 | |
Negative | 1444 (42.2) | |
Positive | 1978 (57.8) | |
HER2 IHC 2 + | 554 | |
Negative | 309 (55.8) | |
Positive | 105 (19) | |
Unclassifiable | 140 (25.2) | |
Receptor subgroups | 3174 | |
ER/PR + HER2− | 1751 (55.2) | |
ER/PR +/− HER2+ | 654 (20.6) | |
Triple negative | 769 (24.2) |
