Figure 4 | Scientific Reports

Figure 4

From: In vitro dual (anticancer and antiviral) activity of the carotenoids produced by haloalkaliphilic archaeon Natrialba sp. M6

Figure 4The alternative text for this image may have been generated using AI.

Cytotoxicity effect of the extracted pigments on human normal and cancer cells. (A) EC50 and EC100 (µg/ml) of pigment extract and the currently used chemotherapy agent (5-FU) towards the human normal cell line (Wi-38) and (B) their IC50 (µg/ml) values against four human cancer cell lines. (C) Selectivity index (SI) of pigments against cancer cells compared with that of 5-FU. (D) Variation in the morphology of normal and cancer cells after treatment with the extracted pigments and 5-FU (magnification ×200). All data are expressed as the mean ± SE with significance (unpaired t-test analysis) at p-value < 0.05*, <0.005**, <0.0005***.

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