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Figure 1

From: Narciclasine, an isocarbostyril alkaloid, has preferential activity against primary effusion lymphoma

Figure 1

Narciclasine and its structural analogs have preferential cytotoxicity towards PEL. (A) Chemical structures of narciclasine, lycoricidine, and lycorine. (B) Indicated panel of cell lines were treated with increasing concentrations of narciclasine, lycoricidine, and lycorine for 72 hours. Cell viability was measured using an MTS (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) assay. An arrow represents cell lines with preferential sensitivity to the compounds. The values shown are mean ± SE. (n = 3) of a representative experiment performed in triplicate for three times.

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