Figure 1

(A) Exemplary visual explanations (superimposed on grey-scaled H&E stain) for the three studied tumour entities. Red denotes positive relevance, i.e. in favour for the prediction of class cancer, while blue denotes negative relevance, i.e. contradicting the prediction of class cancer. Corresponding annotations can be found in Supplemental Fig. 2–4 (blue boxes). The image details illustrate the high-resolution of the computed heatmaps. (B) Corresponding colourbar for the relevance distribution of cancerous tissue classification, which is used throughout the paper.