Table 2 Profile of immune cells in CSF of ALS patients and controls.

From: Peripheral proinflammatory Th1/Th17 immune cell shift is linked to disease severity in amyotrophic lateral sclerosis

Immune cells (%)

ALS N = 16 (Mean ± SD)

controls N = 10 (Mean ± SD)

p-value

Lymphocyte

51.59 ± 13.01

39 ± 12.06

0.048*

CD3 + T cells

12.78 ± 17.51

20.74 ± 26.40

0.280

CD4 + T cells

37.89 ± 24.45

41.76 ± 25.77

0.660

CD8 + T cells

16.09 ± 9.39

27.36 ± 19.0

0.140

CD4 + naïve T cells

15.54 ± 7.90

26.08 ± 17.47

0.250

CD4 + memory T cells

20.77 ± 13.85

13.5 ± 8.41

0.130

CD8 + naïve T cells

38.61 ± 20.72

19.52 ± 16.73

0.014*

CD8 + memory T cells

20.84 ± 14.62

21.13 ± 21.12

0.670

B cells

6.93 ± 2.97

11.03 ± 10.28

0.410

Naïve B cells

83.19 ± 11.2

86.34 ± 6.10

0.620

Memory B cells

13.51 ± 5.78

10.44 ± 6.14

0.280

NK cells

9.59 ± 4.77

8.14 ± 3.40

0.410

NK T cells

2.01 ± 1.78

2.14 ± 1.46

0.530

CD4 + NK T cells

25.61 ± 18.81

22.73 ± 25.48

0.340

CD8 + NK T cells

23.41 ± 15.76

37.27 ± 23.79

0.075

Classical Mo

13.28 ± 7.83

15.18 ± 13.06

0.830

Intermediate Mo

8.89 ± 4.27

7.98 ± 5.63

0.670

Nonclassical Mo

7.50 ± 4.52

14.5 ± 13.28

0.220

SlanDCs

4.34 ± 1.98

4.60 ± 2.57

0.920

BDCA1 + DCs

8.69 ± 7.54

6. 9 ± 3.77

0.980

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