Table 2 Univariate and multivariate Cox-proportional hazard regression analyses for BCR in patients with pathologic T3b after RP.

From: Prognostic value of seminal vesicle invasion on preoperative multi-parametric magnetic resonance imaging in pathological stage T3b prostate cancer

Variables

Univariate

Multivariate

HR

95% CI

P

HR

95% CI

P

Age

1.012

0.979–1.046

0.478

   

BMI

1.066

0.964–1.179

0.212

   

Pre-biopsy PSA

1.011

1.007–1.016

<0.001

1.006

1.000–1.011

0.035

RP GS category

      

  ≤4 + 3

Reference

     

  ≥4 + 4

3.191

2.021–5.037

<0.001

1.461

0.711–3.004

0.302

Pathologic ECE

0.596

0.258–1.380

0.227

   

Pathologic LNI

2.109

1.142–3.894

0.017

0.724

0.313–1.675

0.451

Pathologic PSM

2.115

1.340–3.337

0.001

0.834

0.412–1.687

0.613

Positive SVI on MRI

2.101

1.126–3.924

0.020

1.913

1.003–3.648

0.049

  1. BCR, biochemical recurrence; ECE, extracapsular extension; GS, Gleason score; MRI, magnetic resonance imaging; PSA, prostate-specific antigen; PSM, positive surgical margin; RP, radical prostatectomy; SVI, seminal vesicle invasion.
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