Table 2 Clinical determinants of kidney myostatin expression in patients with type 2 diabetic nephropathy (n = 22).
Biochemical variable | Glomerular myostatin | Tubular myostatin | Interstitial myostatin | |||
|---|---|---|---|---|---|---|
r | p | r | p | r | p | |
Creatinine (mg/dl) | 0.35 | NS | 0.2 | NS | 0.13 | NS |
eGFR (ml/min.1.73m2) | −0.17 | NS | −0.16 | NS | −0.32 | NS |
Urea (mg/dl) | 0.05 | NS | 0.02 | NS | 0.06 | NS |
Uric acid (mg/dl) | 0.09 | NS | 0.01 | NS | 0.003 | NS |
C-Reactive Protein (mg/L) | 0.88 | 0.01 | 0.61 | 0.02 | 0.72 | 0.01 |
Blood glucose (mg/dl) | 0.01 | NS | 0.14 | NS | 0.04 | NS |
HbA1c % | 0.01 | NS | 0.14 | NS | 0.02 | NS |
Duration of diabetes (mo.) | 0.23 | NS | 0.17 | NS | 0.07 | NS |
Fibrinogen (mg/dl) | 0.74 | 0.01 | 0.15 | NS | 0.11 | NS |
Proteinuria (g/24 h) | 0.24 | NS | 0.03 | NS | 0.06 | NS |
