Figure 2 | Scientific Reports

Figure 2

From: Loss-of-function of the long non-coding RNA A830019P07Rik in mice does not affect insulin expression and secretion

Figure 2

P07Rik is downregulated during development and in obese and diabetic mice. P07Rik’s spatial expression pattern measured by qPCR in (A) indicated tissues of adult mice and MIN6 cell line. Glucagon, Insulin (B) and P07Rik (C) expression in α− and β− cells isolated from 3 month old rats. P07Rik expression in (D) rats at P10 and 3 month of age and 13–16 weeks old (E) db/+ and db/db mice and (F) +/+ and ob/ob mice. Data is presented as dots indicating each separate sample and the lines indicating the mean ± SD. Abbreviations: PolII-RNA Polymerase II, GAPDH- Glyceraldehyde-3-Phosphate Dehydrogenase, HPRT-Hypoxanthine Phosphoribosyltransferase. Statistics: *p < 0.05, **p < 0.001, two-tailed t-test. “ND” indicates not detected.

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