Figure 5

P07Rik deletion does not affect islet insulin secretion, content or expression. Islets isolated from WT and flox/flox littermates were stimulated with 2 or 16 mM glucose and insulin secretion (A) and insulin content (B) were measured. (C) Insulin2 relative expression was measured by qPCR in islets of WT and flox/flox littermates. Data is presented as dotplot indicating each separate sample and the lines indicating the mean ± SD. Abbreviations: HPRT-Hypoxanthine Phosphoriboslytransferase. Statistics: NS- p > 0.05, two-tailed t-test.