Figure 1

Schematic of pulse sequence and prescription of imaging slices. Pulse sequence consisted of two loops. The outer perfusion loop (top) was acquired with interleaved tagging (SS) and control (NS) adiabatic inversion pulse followed by PLD and radial acquisition of perfusion imaging slice (slice 1). Inner loop consisted of multi-echo GRE pulse sequence implemented during the PLD delay to get multi echo images for T2* calculation. Five echo images were acquired during one outer perfusion loop with echo times = 2.2, 5.0, 7.8, 10.6 and 13.4 ms. Perfusion slice was selected 3 cm proximal to the T2* slice which accounts for the incoming arterial blood flow direction.