Figure 3
From: Effect of UVC Irradiation on the Oxidation of Histidine in Monoclonal Antibodies
Base peak ion chromatograms of angiotensin II [DRVYIHPF; retention time 8.2 min, m/z 523.79 (z = 2)] (a), and its oxidation products after UVC irradiation in H216O (b) and in H218O (c). The retention times and m/z values of the peaks are P1, P1′: 6.7 min, m/z 379.72 (z = 2); P2, P2′: 7.5 min, m/z 263.13 (z = 1); P3, P3′: 8.7 min, m/z 501.78 (z = 2); P4, P4′: 9.1 min, m/z 512.27 (z = 2); and P5, P5′: 9.3 min, m/z 512.76 (z = 2, P5) and 513.76 (z = 2, P5′).
