Figure 1 | Scientific Reports

Figure 1

From: Fasentin diminishes endothelial cell proliferation, differentiation and invasion in a glucose metabolism-independent manner

Figure 1

Fasentin inhibits endothelial, tumour and fibroblast cell growth. (a) Chemical structure of fasentin. (b) Dose-response curves showing the effect of fasentin on the in vitro growth of different cell lines after 72 h treatment from low density seeding conditions. Cell number is represented as the percentage of cells compared to the condition containing no drug. Concentrations are represented in logarithmic scale. (c) HMECs were seeded at high density and allowed to attach for 24 h. Then, different concentrations of fasentin were added and cell number was monitored using Trypan blue and a Neubauer chamber at 0, 4, 7, 16 and 24 h. Trypan blue allowed to exclude dead cells. Data are expressed as means ± SD of three independent experiments.

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