Figure 2
From: iMM1865: A New Reconstruction of Mouse Genome-Scale Metabolic Model
Mouse-specific reactions which were added into iMM1865. (A) Synthesis ascorbate (vitamin C) from glucose. The last enzyme of this pathway is not available in human. (B) There are three sub-pathways for threonine degradation. Human cells do not contain L-threonine 3-dehydrogenase enzyme. So breakdown of L-threonine into pyruvate does not occur. (C) A Sub-pathway of amino sugar metabolism which was added into iMM1865. Blue arrow: reactions exist in both Recon3D and iMM1865; Red arrow: reactions just exist in iMM1865; Dashed arrow: reactions are part of metabolic pathway; Black metabolites/enzymes: metabolites/enzymes exist in both Recon3D and iMM1865; Blue metabolites: metabolites just exist in iMM1865; Red enzymes: enzymes just exist in iMM1865. ER: endoplasmic reticulum.
