Figure 8
Phylogenetic analysis of 62 response regulators (left panel) and 65 sensory kinases (right panel). Sequences associated with established gene clusters are identified by the compound name followed by the genus of the corresponding strain; characterized S. coelicolor proteins are identified by the protein name followed by the SCO code; and N. gerenzanensis sequences are denoted by the SBO or SBP codes. The branches associated with the Van-and Dbv-related TCSs are identified by green and orange boxes, respectively. Green and red arrows indicate the adjacent members of two different, uncharacterized N. gerenzanensis TCSs closely associated with the Dbv branches. Sequences associated with N. gerenzanensis biosynthetic gene clusters, as identified by AntiSMASH 5.042, have a yellow highlight.
