Table 5 Kinetic Profile of different medicated polymeric MNs formulations.

From: Characterization and Pharmacological Evaluation of Anti-Cellulite Herbal Product(s) Encapsulated in 3D-Fabricated Polymeric Microneedles

Formulation

Zero-order

First-order

Higushi-diffusion

Korsemeyer–Peppas

Possible kinetics order & mechanism of the drug release

r

k

R

k

r

k

r

k

n

F1

0.9546

0.8869

0.9959

0.0283

0.9903

10.908

0.9889

0.0485

0.7358

First order kinetics, Case II transport.

F2

0.8969

0.7981

0.9828

0.0392

0.9603

10.129

0.9997

0.0812

0.6984

First order kinetics, Case II transport

F3

0.9345

0.7765

0.9911

0.0295

0.9788

9.641

0.9971

0.1505

0.4076

First order kinetics, Fickian release

F4

0.9146

0.7568

0.9931

0.0404

0.9678

9.494

0.9995

0.1905

0.3501

First order kinetics, Fickian release

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