Table 6 Effect of V. agnus-castus and T. indica extracts on TNF – α, MPO activity as well as GSH and MDA tissue content in HFCS-treated guinea pigs.

From: Characterization and Pharmacological Evaluation of Anti-Cellulite Herbal Product(s) Encapsulated in 3D-Fabricated Polymeric Microneedles

Groups

TNF-α Pg/g.tissue

MPO U/g.tissue

GSH mg/g.tissue

MDA mol/g.tissue

Normal Control

85.77 ± 3.48

16.49 ± 0.82

306.11 ± 22.12

94.45 ± 7.92

HFCS

145.91 ± 5.93a

57.70 ± 2.87a

168.47 ± 11.87a

152.17 ± 10.17a

V.agnus-castus (200 mg/kg)

107.99 ± 4.38b

42.46 ± 1.72b

296.28 ± 18.97b

96.53 ± 6.12b

T.indica (200 mg/kg)

92.79 ± 3.78b

24.43 ± 0.99bc

355.42 ± 24.14b

82.04 ± 5.44b

  1. Data are presented as the mean ± SEM; asignificantly different from normal control group; P ≤ 0.05; bsignificantly different from HFCS induction group, P ≤ 0.05; csignificantly different from V. agnus-castus group at P ≤ 0.05. TNF-α: Pg/g. tissue; MPO: U/g. tissue; GSH mg/g.tissue; MDA: nmol/g.tissue.