Figure 4 | Scientific Reports

Figure 4

From: Fluid shear stress coupled with narrow constrictions induce cell type-dependent morphological and molecular changes in SK-BR-3 and MDA-MB-231 cells

Figure 4

Genome integrity analysis of SK-BR-3 and MDA-MB-231 cells post-circulation, -confinement and -constrictions at a constant applied pressure of 10 kPa. (a) DAPI (blue) and γ-H2AX (green) staining of SK-BR-3 (top row) and MDA-MB-231 (bottom row) cells. (b) Box plot showing all points (minimum to maximum) of nuclear to total intensity of γ-H2AX for both cell types. Kolmogorov-Smirnov test. *significance level at 0.033; **significance level at 0.002; ***significance level < 0.001; ns, not significant.

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