Table 1 Statistical methods for the detection of peak changes.

From: Limits in the detection of m6A changes using MeRIP/m6A-seq

Method

Read count distribution

Publication

MeTDiff

Poisson

Cui et al. (2018)

Quad-negative binomial (QNB)

Negative binomial

Liu et al. (2017)

GLM (DESeq. 2)

Negative binomial

based on Park et al. (2014) method for HITS-CLIP

GLM (edgeR)

Negative binomial