Table 1 Baseline characteristics of the early-stage breast cancer patients included in the study.

From: Dysregulated EGFR pathway in serum in early-stage breast cancer patients: A case control study

 

Breast cancer patients, n (%)

n

311

Age at time of primary surgery

  <50 years

65 (21%)

  50–69 years

197 (63%)

  ≥70 years

49 (16%)

Tumor size

  T1 ≤ 20 mm

175 (56%)

  T2 > 20 ≤ 50 mm

132 (42%)

  T3 > 50 mm

4 (1.3%)

Histological typea

  Ductal

276 (89%)

  Lobular

15 (4.8%)

  Other

20 (6.4%)

Tumor grade

  Grade I

71 (23%)

  Grade II

141 (45%)

  Grade III

78 (25%)

  Unknown

21 (6.8%)

Lymph node metastasis

  N0 = 0 nodes

155 (50%)

  N1 = 1–3 nodes

111 (36%)

  N2–3 ≥ 4 nodes

45 (14%)

Estrogen receptor status

  Negative (<10%)

58 (19%)

  Positive (10–100%)

253 (81%)

HER2 IHC/FISH statusb

  Negative

248 (80%)

  Positive

49 (16%)

  Unknown

14 (4.5%)

Progesterone receptor status

  Negative (<10%)

91 (29%)

  Positive (10–100%)

183 (59%)

  Unknown

37 (12%)

Triple negative

  Yes

33 (11%)

  No

227 (73%)

  Unknown

51 (16%)

  1. aIn cases where more than one histological type was detected in the tumor, the histological type was considered to be ductal if the tumor was either both ductal and lobular or ductal and other. bHER2 IHC/FISH: Status of human epidermal growth factor receptor 2 (HER2) in breast cancer tumor evaluated by immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). Positive: IHC 3+ or IHC 2+ and FISH ≥ 2. Negative: IHC 0 or IHC 1+ or IHC 2+ and FISH < 2.