Table 2 Effects of maternal bilateral uterine artery ligation (BUAL) surgery on fat depots of male and female offspring fed a normal diet (ND) or western diet (WD) chronically.

From: Late-pregnancy uterine artery ligation increases susceptibility to postnatal Western diet-induced fat accumulation in adult female offspring

Organ

Weight

ND

WD

P value

Sham

BUAL

Sham

BUAL

BUAL

Diet

Interaction

Male Offspring

Retroperitoneal fat

Absolute (g)

24.14 ± 2.88

21.10 ± 2.52

43.02 ± 5.829

36.17 ± 3.09

0.382

0.0001

0.436

Relative (%BW)

3.61 ± 0.19

3.61 ± 0.22

5.43 ± 0.469

5.09 ± 0.24

0.685

0.0002

0.553

Epididymal fat

Absolute (g)

11.01 ± 1.84

10.06 ± 1.22

17.05 ± 2.80

17.44 ± 2.18

0.844

0.0008

0.488

Relative (%BW)

1.62 ± 0.18

1.71 ± 0.10

2.18 ± 0.31

2.47 ± 0.25

0.595

0.006

0.505

Mesenteric fat

Absolute (g)

11.25 ± 1.55

10.94 ± 1.27

14.79 ± 1.22

13.92 ± 1.59

0.826

0.001

0.503

Relative (%BW)

1.67 ± 0.13

1.87 ± 0.13

1.90 ± 0.10

1.95 ± 0.13

0.374

0.186

0.454

Omental fat

Absolute (g)

2.54 ± 0.41

2.85 ± 0.72

4.23 ± 0.61

3.94 ± 0.50

0.980

0.0005

0.238

Relative (%BW)

0.37 ± 0.04

0.47 ± 0.10

0.53 ± 0.06

0.55 ± 0.04

0.445

0.021

0.366

Female Offspring

Retroperitoneal fat

Absolute (g)

30.79 ± 4.23

19.78 ± 2.62

39.30 ± 4.23

40.34 ± 2.069

0.326

P < 0.001

0.009

Relative (%BW)

7.58 ± 0.66

6.34 ± 0.69

8.34 ± 0.73

9.02 ± 0.30

0.7156

0.013

0.116

Mesenteric fat

Absolute (g)

7.76 ± 1.22

4.38 ± 0.76*

9.56 ± 1.01

11.61 ± 0.719

0.638

P < 0.001

0.002

Relative (%BW)

1.90 ± 0.18

1.40 ± 0.21

2.04 ± 0.19

2.61 ± 0.179

0.843

0.003

0.010

Omental fat

Absolute (g)

2.44 ± 0.32

1.23 ± 0.12*

2.74 ± 0.49

3.50 ± 0.549

0.669

0.001

0.004

Relative (%BW)

0.60 ± 0.05

0.40 ± 0.04

0.57 ± 0.09

0.79 ± 0.12

0.894

0.017

0.005

  1. *P ≤ 0.05 compares sham and BUAL in same diet group. P < 0.05, P < 0.01, 9P < 0.001 compares ND and WD in the same surgery group.