Figure 3
Graphs showing (a) Percentage of cells with intracellular α-syn in the AON of PD OFBs (n = 11), where, 7.78% ± 5.22% of microglia, 3.41% ± 2.74% of pericytes, 1.97% ± 1.17% of astrocytes and 0% of oligodendrocytes contained intracellular α-syn. Whereas, 2.25% ± 2.41% of neurons contained small α-syn inclusions, 6.38% ± 6.83% of neurons contained Lewy bodies, giving a total of 8.68% ± 9.34% α-syn containing neurons overall. (b) Number of cells with intracellular α-syn in the AON/mm2 (n = 11), microglia (14.02 ± 10.23 cells/mm2), astrocytes (5.09 ± 3.55 cells/mm2), pericytes (4.93 ± 3.60 cells/mm2) and oligodendrocytes (0 cells /mm2). Neurons either contained small α-syn inclusions (8.84 ± 8.56 cells/mm2) or Lewy bodies (24.10 ± 25.25 cells/mm2) comprising a total number of neurons (32.49 ± 33.69 cells/mm2) containing intracellular α-syn. Data presented as mean ± SD.
